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805P Tumor-informed ctDNA detection as a predictive marker for postoperative residual disease in epithelial ovarian cancer: A feasibility study
Background
Complete tumor resection is the most relevant prognostic factor for overall survival in high grade serous ovarian cancer …
Christoph Grimm
,
Valentina Paspalj
,
Magdalena Postl
,
Lao H. Saal
,
Christian Brueffer
,
Nuria Segui Gracia
,
Miguel Alcaide
,
Stephan Polterauer
,
Lucia Oton
,
Yilun Chen
,
Gerda Hofstetter
,
Leonhard Müllauer
DOI
PDF
#898 Tumor-informed ctDNA detection as a marker for postoperative residual disease in epithelial ovarian cancer – results of a feasibility study
Introduction/Background
Complete tumor resection is the most relevant prognostic factor for overall survival in high grade serous …
Magdalena Postl
,
Valentina Paspalj
,
Christian Brueffer
,
Nuria Segui Gracia
,
Miguel Alcaide
,
Lucia Oton
,
Yilun Chen
,
Lao H. Saal
,
Gerda Hofstetter
,
Leonhard Müllauer
,
Stephan Polterauer
,
Christoph Grimm
DOI
PDF
Abstract 5710: Detection and monitoring of t(11;14) in liquid biopsies from patients with relapsed/refractory multiple myeloma treated with venetoclax-based regimens
Venetoclax (Ven) is a selective B-cell lymphoma 2 inhibitor being studied in t(11;14)+ relapsed/refractory multiple myeloma (MM). …
Xiaotong Li
,
Lao H. Saal
,
Christian Brueffer
,
Yilun Chen
,
Johanna Asklin
,
Saman Alvi
,
Srinivas Venkatram
,
Jeremy A. Ross
DOI
2022-RA-627-ESGO: Preoperative circulating tumor DNA level is associated to poor overall survival in patients with ovarian cancer
Introduction/Background
Circulating tumor DNA (ctDNA), which is shed from tumor cells into the blood, is a promising minimal-invasive …
Arturas Dobilas
,
Pia Leandersson
,
Yilun Chen
,
Miguel Alcaide
,
Christian Brueffer
,
Lao H. Saal
,
Christer Borgfeldt
DOI
PDF
Preoperative circulating tumor DNA level is associated to poor overall survival in patients with ovarian cancer
Background
Circulating tumor DNA (ctDNA), which is shed from tumor cells into the blood, is a promising minimal-invasive method for …
Arturas Dobilas
,
Yilun Chen
,
Miguel Alcaide
,
Christian Brueffer
,
Pia Leandersson
,
Lao H. Saal
,
Christer Borgfeldt
DOI
PDF
Clinical associations of ESR2 (estrogen receptor beta; ERβ) expression across thousands of primary breast tumors
Estrogen receptor alpha (ERα, encoded by ESR1) is a well-characterized transcription factor expressed in more than 75% of breast tumors …
Hina Dalal
,
Malin Dahlgren
,
Sergii Gladchuk
,
Christian Brueffer
,
Sofia K. Gruvberger-Saal
,
Lao H. Saal
DOI
PDF
Dataset
Preexisting Somatic Mutations of Estrogen Receptor Alpha (ESR1) in Early-Stage Primary Breast Cancer
Background
More than three-quarters of primary breast cancers are positive for estrogen receptor alpha (ER; encoded by the gene
ESR1
), …
Malin Dahlgren
,
Anthony M. George
,
Christian Brueffer
,
Sergii Gladchuk
,
Yilun Chen
,
Johan Vallon-Christersson
,
Cecilia Hegardt
,
Jari Häkkinen
,
Lisa Rydén
,
Martin Malmberg
,
Christer Larsson
,
Sofia K. Gruvberger-Saal
,
Anna Ehinger
,
Niklas Loman
,
Åke Borg
,
Lao H. Saal
DOI
PDF
Dataset
Press Release
RNA Sequencing for Molecular Diagnostics in Breast Cancer
Breast cancer is the most common type of cancer in women and, in Sweden, is the most deadly second only to lung cancer. While treatment …
Christian Brueffer
PDF
Code
LUCRIS Project
Features of increased malignancy in eosinophilic clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) is the most common form of renal cancer. Due to inactivation of the von Hippel–Lindau tumour …
Helén Nilsson
,
David Lindgren
,
Håkan Axelson
,
Christian Brueffer
,
Lao H. Saal
,
Jaana Lundgren
,
Martin Johansson
DOI
PDF
Abstract CT074: Pre-existing ESR1 mutations in early-stage primary breast cancer predict failure of endocrine therapy and poor survival
Background
More than three-quarters of primary breast cancers are positive for estrogen receptor alpha (ER; encoded by the gene
ESR1
), …
Malin Dahlgren
,
Anthony M. George
,
Christian Brueffer
,
Sergii Gladchuk
,
Yilun Chen
,
Johan Vallon-Christersson
,
Cecilia Hegardt
,
Jari Häkkinen
,
Lisa Rydén
,
Martin Malmberg
,
Christer Larsson
,
Sofia K. Gruvberger-Saal
,
Anna Ehinger
,
Niklas Loman
,
Åke Borg
,
Lao H. Saal
DOI
»
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