Publications
People
Contact
Digital PCR
805P Tumor-informed ctDNA detection as a predictive marker for postoperative residual disease in epithelial ovarian cancer: A feasibility study
Background
Complete tumor resection is the most relevant prognostic factor for overall survival in high grade serous ovarian cancer …
Christoph Grimm
,
Valentina Paspalj
,
Magdalena Postl
,
Lao H. Saal
,
Christian Brueffer
,
Nuria Segui Gracia
,
Miguel Alcaide
,
Stephan Polterauer
,
Lucia Oton
,
Yilun Chen
,
Gerda Hofstetter
,
Leonhard Müllauer
DOI
PDF
#898 Tumor-informed ctDNA detection as a marker for postoperative residual disease in epithelial ovarian cancer – results of a feasibility study
Introduction/Background
Complete tumor resection is the most relevant prognostic factor for overall survival in high grade serous …
Magdalena Postl
,
Valentina Paspalj
,
Christian Brueffer
,
Nuria Segui Gracia
,
Miguel Alcaide
,
Lucia Oton
,
Yilun Chen
,
Lao H. Saal
,
Gerda Hofstetter
,
Leonhard Müllauer
,
Stephan Polterauer
,
Christoph Grimm
DOI
PDF
Abstract 5710: Detection and monitoring of t(11;14) in liquid biopsies from patients with relapsed/refractory multiple myeloma treated with venetoclax-based regimens
Venetoclax (Ven) is a selective B-cell lymphoma 2 inhibitor being studied in t(11;14)+ relapsed/refractory multiple myeloma (MM). …
Xiaotong Li
,
Lao H. Saal
,
Christian Brueffer
,
Yilun Chen
,
Johanna Asklin
,
Saman Alvi
,
Srinivas Venkatram
,
Jeremy A. Ross
DOI
2022-RA-627-ESGO: Preoperative circulating tumor DNA level is associated to poor overall survival in patients with ovarian cancer
Introduction/Background
Circulating tumor DNA (ctDNA), which is shed from tumor cells into the blood, is a promising minimal-invasive …
Arturas Dobilas
,
Pia Leandersson
,
Yilun Chen
,
Miguel Alcaide
,
Christian Brueffer
,
Lao H. Saal
,
Christer Borgfeldt
DOI
PDF
Preoperative circulating tumor DNA level is associated to poor overall survival in patients with ovarian cancer
Background
Circulating tumor DNA (ctDNA), which is shed from tumor cells into the blood, is a promising minimal-invasive method for …
Arturas Dobilas
,
Yilun Chen
,
Miguel Alcaide
,
Christian Brueffer
,
Pia Leandersson
,
Lao H. Saal
,
Christer Borgfeldt
DOI
PDF
Preexisting Somatic Mutations of Estrogen Receptor Alpha (ESR1) in Early-Stage Primary Breast Cancer
Background
More than three-quarters of primary breast cancers are positive for estrogen receptor alpha (ER; encoded by the gene
ESR1
), …
Malin Dahlgren
,
Anthony M. George
,
Christian Brueffer
,
Sergii Gladchuk
,
Yilun Chen
,
Johan Vallon-Christersson
,
Cecilia Hegardt
,
Jari Häkkinen
,
Lisa Rydén
,
Martin Malmberg
,
Christer Larsson
,
Sofia K. Gruvberger-Saal
,
Anna Ehinger
,
Niklas Loman
,
Åke Borg
,
Lao H. Saal
DOI
PDF
Dataset
Press Release
Abstract CT074: Pre-existing ESR1 mutations in early-stage primary breast cancer predict failure of endocrine therapy and poor survival
Background
More than three-quarters of primary breast cancers are positive for estrogen receptor alpha (ER; encoded by the gene
ESR1
), …
Malin Dahlgren
,
Anthony M. George
,
Christian Brueffer
,
Sergii Gladchuk
,
Yilun Chen
,
Johan Vallon-Christersson
,
Cecilia Hegardt
,
Jari Häkkinen
,
Lisa Rydén
,
Martin Malmberg
,
Christer Larsson
,
Sofia K. Gruvberger-Saal
,
Anna Ehinger
,
Niklas Loman
,
Åke Borg
,
Lao H. Saal
DOI
Plasma circulating tumor DNA as a genomic biomarker for ovarian cancer
Introduction
Ovarian cancer (OC) remains the most lethal disease among gynecological malignancies as most patients are diagnosed in an …
Yoshiko Nanki
,
Anthony M. George
,
Yilun Chen
,
Christian Brueffer
,
Akira Hirasawa
,
Tatsuyuki Chiyoda
,
Tomoko Akahane
,
Daisuke Aoki
,
Lao H. Saal
Detection of circulating tumor cells and circulating tumor DNA before and after mammographic breast compression in a cohort of breast cancer patients scheduled for neoadjuvant treatment
Purpose
It is not known if mammographic breast compression of a primary tumor causes shedding of tumor cells into the circulatory …
Daniel Förnvik
,
Kristina E. Aaltonen
,
Yilun Chen
,
Anthony M. George
,
Christian Brueffer
,
Robert Rigo
,
Niklas Loman
,
Lao H. Saal
,
Lisa Rydén
DOI
PDF
Abstract P4-09-03: On the development and clinical value of RNA-sequencing-based classifiers for prediction of the five conventional breast cancer biomarkers: A report from the population-based multicenter SCAN-B study
Background
In early breast cancer, five histopathological biomarkers are part of current clinical routines and used for determining …
Christian Brueffer
,
Johan Vallon-Christersson
,
Dorthe Grabau
,
Anna Ehinger
,
Jari Häkkinen
,
Cecilia Hegardt
,
Janne Malina
,
Yilun Chen
,
Pär-Ola Bendahl
,
Jonas Manjer
,
Martin Malmberg
,
Christer Larsson
,
Niklas Loman
,
Lisa Rydén
,
Åke Borg
,
Lao H. Saal
DOI
Cite
×